abstract：:Post-operative adhesions are a significant complication of all abdominal surgical procedures. The major strategies for adhesion prevention in gynaecological surgery are focused on the optimization of surgical technique and use of anti-adhesive agents, which fall into two main categories: pharmacological agents and bar...

journal_title：Reproductive biomedicine online

authors： Pados G,Venetis CA,Almaloglou K,Tarlatzis BC

更新日期：2010-09-01 00:00:00

abstract：:This report aimed to examine the effects of atosiban on pregnancy outcome after IVF-embryo transfer. A prospective, randomized, placebo-controlled clinical study was performed. A total of 180 women undergoing intracytoplasmic sperm injection who had top-quality embryos were randomly allocated into treatment and contro...

journal_title：Reproductive biomedicine online

authors： Moraloglu O,Tonguc E,Var T,Zeyrek T,Batioglu S

更新日期：2010-09-01 00:00:00

abstract：:In 2006 the Dutch Society for Clinical Embryologists (KLEM) approached the Netherlands Standardisation Institute (NEN) for advice regarding the lack of safety and quality specifications for medical devices used in assisted reproductive technology. A project plan was drafted in accordance with NEN-standardized methods ...

journal_title：Reproductive biomedicine online

authors： Wetzels AM,Kastrop PM,NTA-Working Group.

更新日期：2010-08-01 00:00:00

abstract：:The aetiology of endometriosis, a gynaecological disease defined by the histological presence of endometrial glands and stroma outside the uterine cavity, is still open to debate. Research has recently found evidence for endometriosis in human female fetuses at different gestational ages. This paper reports a new case...

journal_title：Reproductive biomedicine online

authors： Signorile PG,Baldi F,Bussani R,D'Armiento M,De Falco M,Boccellino M,Quagliuolo L,Baldi A

更新日期：2010-07-01 00:00:00

abstract：:Gonadotrophin-releasing hormone (GnRH) agonists and antagonists have been widely used to prevent premature LH surge during ovarian stimulation. However, studies have shown a significantly lower serum oestradiol concentration on the day of human chorionic gonadotrophin administration for cycles using GnRH antagonist. T...

journal_title：Reproductive biomedicine online

authors： Khalaf M,Mittre H,Levallet J,Hanoux V,Denoual C,Herlicoviez M,Bonnamy PJ,Benhaim A

更新日期：2010-07-01 00:00:00

abstract：:This study investigated the role of the leptin system in human oocyte maturation and its prognostic value for IVF outcome. The protein concentrations of leptin and soluble leptin receptor in follicular fluid were determined and the free leptin index (FLI) were established. Additionally, mRNA expression levels of diffe...

journal_title：Reproductive biomedicine online

authors： van Tol HT,Vernooij JC,Colenbrander B,Gutknecht D,Macklon NS,Roelen BA

更新日期：2010-06-01 00:00:00

abstract：:This study aimed to investigate how hyperandrogenism affects early folliculogenesis. Hyperandrogenism was induced in prepuberal female BALB/c mice by daily s.c. injection of dehydroepiandrosterone (60 mg/kg body weight in 0.1 ml sesame oil) for 10 consecutive days. Although hyperandrogenism increased the growth rate o...

journal_title：Reproductive biomedicine online

authors： Belgorosky D,Sander VA,Yorio MP,Faletti AG,Motta AB

更新日期：2010-06-01 00:00:00

abstract：:Aromatase inhibitors can be utilized to minimize oestrogen exposure in breast cancer patients undergoing gonadotrophin stimulation. This retrospective-prospective study determined whether using a gonadotrophin-releasing hormone agonist (GnRHa) trigger instead of human chorionic gonadotrophin (HCG) would reduce oestrog...

journal_title：Reproductive biomedicine online

authors： Oktay K,Türkçüoğlu I,Rodriguez-Wallberg KA

更新日期：2010-06-01 00:00:00

abstract：:Epigenetic alterations at several maternal loci have been associated with imprinting disorders in children conceived using assisted reproductive technologies. To date, epimutations at paternal loci have been observed in the spermatozoa of infertile men, but there is little evidence of paternal epimutations in babies c...

journal_title：Reproductive biomedicine online

authors： Chopra M,Amor DJ,Sutton L,Algar E,Mowat D

更新日期：2010-06-01 00:00:00

abstract：:Anovulatory women can prove extremely challenging patients in the fertility clinic, particularly if they are unresponsive to standard protocols of clomiphene citrate. Katayama and colleagues now report (in this issue) an intriguing option, which yielded surprisingly high success rates in 16 selected young (age <36year...

journal_title：Reproductive biomedicine online

authors： Ahuja KK,Andonov M,Linara E,Simons E

更新日期：2010-06-01 00:00:00

abstract：:This study tested in-vitro maturation (IVM) as a complementary strategy to improve the mature oocyte yield of breast cancer patients undergoing ovarian stimulation for fertility preservation. Secondary analysis of prospectively collected data is performed for 32 breast cancer patients undergoing oocyte or embryo cryop...

journal_title：Reproductive biomedicine online

authors： Oktay K,Buyuk E,Rodriguez-Wallberg KA,Sahin G

更新日期：2010-05-01 00:00:00

abstract：:The possible relationship between endogenous LH concentrations and clinical outcome was evaluated in 750 patients treated with a standardized gonadotrophin-releasing hormone (GnRH) antagonist and recombinant FSH (rFSH)-only protocol. Serum LH concentrations were measured during stimulation by a central laboratory and ...

journal_title：Reproductive biomedicine online

authors： Doody K,Devroey P,Gordon K,Witjes H,Mannaerts B

更新日期：2010-04-01 00:00:00

abstract：:This study evaluated the effect of two oxygen concentrations (20 and 5%) on bovine embryo development (kinetics of first cleavage and blastocyst development) during maturation (M) and fertilization (F) and analysed differences in gene expression between cumulus-oocyte complexes (COC) matured at 5 or 20% oxygen and the...

journal_title：Reproductive biomedicine online

authors： Bermejo-Alvarez P,Lonergan P,Rizos D,Gutiérrez-Adan A

更新日期：2010-03-01 00:00:00

abstract：:This is a report of a 6-year follow-up of a male patient's semen parameters during heavy chronic alcohol intoxication and after withdrawal. A slowly progressive negative impact of alcohol could be observed: isolated moderate teratozoospermia was firstly noted followed by oligoasthenoteratospermia. Then a severe worsen...

journal_title：Reproductive biomedicine online

authors： Sermondade N,Elloumi H,Berthaut I,Mathieu E,Delarouzière V,Ravel C,Mandelbaum J

更新日期：2010-03-01 00:00:00

abstract：:The non-classical major histocompatibility complex (MHC) class Ib antigens, termed HLA-G and HLA-E, have been associated with fetal maternal tolerance. The role of HLA-G in the preimplantation embryo remains unclear although immunoprotection, adhesion and cell signalling mechanisms have been suggested. Unlike HLA-G, H...

journal_title：Reproductive biomedicine online

authors： Shaikly V,Shakhawat A,Withey A,Morrison I,Taranissi M,Dealtry GB,Jabeen A,Cherry R,Fernández N

更新日期：2010-02-01 00:00:00

abstract：:Surgical treatment of ovarian endometriosis has been associated with damage to the ovarian tissue and premature ovarian failure in young patients. A modified surgical technique that combines cyst excision with ablation for the surgical treatment of ovarian endometriomas is presented, with the aim of reducing possible ...

journal_title：Reproductive biomedicine online

authors： Muzii L,Panici PB

更新日期：2010-02-01 00:00:00

abstract：:Participation in external quality control (EQC) programmes is recommended by various scientific societies. Results from an EQC programme for embryology laboratories are presented. This 5-year programme consisted of the annual delivery of (i) materials to test toxicity and (ii) a DVD/CD-ROM with images of zygotes and e...

journal_title：Reproductive biomedicine online

authors： Castilla JA,Ruiz de Assín R,Gonzalvo MC,Clavero A,Ramírez JP,Vergara F,Martínez L

更新日期：2010-01-01 00:00:00

abstract：:Recent studies have given conflicting results regarding growth in children born following assisted reproductive treatments up to the age of 18years. It has been suggested that children conceived via IVF may be taller than naturally conceived children and that this may due to subtle epigenetic alteration of imprinted g...

journal_title：Reproductive biomedicine online

authors： Basatemur E,Shevlin M,Sutcliffe A

更新日期：2010-01-01 00:00:00

abstract：:This study aimed to investigate whether the spermatozoa-zona pellucida binding test is able to select spermatozoa with higher fertilization potential and higher rate of successful embryo development. This prospective study was performed with metaphase II (MII) oocytes retrieved from couples undergoing intracytoplasmic...

journal_title：Reproductive biomedicine online

authors： Paes Almeida Ferreira de Braga D,Iaconelli A Jr,Cássia Sávio de Figueira R,Madaschi C,Semião-Francisco L,Borges E Jr

更新日期：2009-12-01 00:00:00

abstract：:Protein kinase B (PKB/Akt), a serine/threonine kinase, regulates the function of many cellular proteins involved in apoptosis and proliferation. It was postulated that there is a higher Akt activity in endometriosis compared with normal endometrium, and that oestrogen may be one of the factors responsible for the high...

journal_title：Reproductive biomedicine online

authors： Cinar O,Seval Y,Uz YH,Cakmak H,Ulukus M,Kayisli UA,Arici A

更新日期：2009-12-01 00:00:00

abstract：:Preimplantation genetic diagnosis (PGD) is usually used to establish a non-affected pregnancy for those couples facing a genetic risk of having an affected child. However, an invasive test is still recommended to all PGD patients due to the risk of misdiagnosis. The discovery of cell-free fetal DNA in maternal plasma ...

journal_title：Reproductive biomedicine online

authors： Li Y,Altarescu G,Renbaum P,Eldar-Geva T,Levy-Lahad E,Margalioth EJ,Zhong X,Hahn S,Holzgreve W

更新日期：2009-11-01 00:00:00

abstract：:The anti-oestrogenic activity of clomiphene citrate (CC) on the cervical mucous and endometrium may be the reason for the relatively low pregnancy rates in CC induction cycles. Various follicular-phase supplements have been tried to improve cycle outcome in these patients. This study compared follicular-phase suppleme...

journal_title：Reproductive biomedicine online

authors： Shahin AY,Ismail AM,Shaaban OM

更新日期：2009-10-01 00:00:00

abstract：:The association between polycystic ovary syndrome (PCOS) and recurrent miscarriage (RM) has been long established, but the relative importance of this condition as a cause of RM is far from clear. Previous studies on the prevalence of PCOS in RM have been hampered by a lack of objective and universally accepted criter...

journal_title：Reproductive biomedicine online

authors： Cocksedge KA,Saravelos SH,Metwally M,Li TC

更新日期：2009-10-01 00:00:00

abstract：:Aurora kinases comprise a family of phosphoproteins performing multiple functions in mitosis and meiosis. Because Aurora kinase B (AURKB) expression is altered in aged oocytes and there is only limited information on its function in meiosis, it was decided to study the spatial distribution and co-localization of AURKB...

journal_title：Reproductive biomedicine online

authors： Vogt E,Kipp A,Eichenlaub-Ritter U

更新日期：2009-09-01 00:00:00

abstract：:X-linked genetic diseases include a wide range of disorders such as the dystrophinopathies. Additionally in some rare genetic diseases, severity of expression is gender dependent. Prevention of such disorders usually involves prenatal diagnosis and termination of affected pregnancies, while preimplantation genetic dia...

journal_title：Reproductive biomedicine online

authors： Christofidou C,Sofocleous C,Vrettou C,Destouni A,Traeger-Synodinos J,Kekou K,Palmer G,Kokkali G,Mavrou A,Kitsiou S,Kanavakis E

更新日期：2009-09-01 00:00:00

abstract：:The maturation medium for in-vitro oocyte maturation is usually supplemented with serum. However, supplementation with serum from pregnant women adversely affects the outcome of in-vitro maturation. The purpose of the study was to assess if growth factors or granulosa cell co-culture could overcome the adverse effects...

journal_title：Reproductive biomedicine online

authors： Lin YH,Hwang JL,Seow KM,Huang LW,Chen HJ,Tzeng CR

更新日期：2009-08-01 00:00:00

abstract：:Chromosome abnormalities are common in oocytes derived from patients undergoing IVF treatment. The proportion of oocytes displaying aneuploidy is closely related to maternal age and may exceed 60% in patients over 40 years old. However, little information currently exists concerning the incidence of such anomalies in ...

journal_title：Reproductive biomedicine online

authors： Fragouli E,Escalona A,Gutiérrez-Mateo C,Tormasi S,Alfarawati S,Sepulveda S,Noriega L,Garcia J,Wells D,Munné S

更新日期：2009-08-01 00:00:00

abstract：:There is an ongoing debate over the optimal dose of urinary HCG (u-HCG) that can trigger final oocyte maturation, leading to higher IVF success rate without increasing the risk of ovarian hyperstimulation syndrome (OHSS). A systematic review was conducted of all studies that compared the effect of at least two doses o...

journal_title：Reproductive biomedicine online

authors： Tsoumpou I,Muglu J,Gelbaya TA,Nardo LG

更新日期：2009-07-01 00:00:00

abstract：:Several surgical treatment modalities have been described in cases of isolated or multiple ovarian endometriotic cysts. The aim of this preliminary study was to investigate and test the efficacy of ethanol sclerotherapy (EST) for recurrent endometriotic cysts, before ovarian stimulation in infertile patients with an a...

journal_title：Reproductive biomedicine online

authors： Yazbeck C,Madelenat P,Ayel JP,Jacquesson L,Bontoux LM,Solal P,Hazout A

更新日期：2009-07-01 00:00:00

abstract：:Over the past decade, the number of reported live births resulting from oocyte cryopreservation has rapidly increased. To appreciate the true number of children born, verified live births were tabulated and assessed. A literature search was performed; authors were then contacted to verify birth outcomes and provide up...

journal_title：Reproductive biomedicine online

authors： Noyes N,Porcu E,Borini A

更新日期：2009-06-01 00:00:00

abstract：:Arrest of proliferation is one of the prerequisites for differentiation of cytotrophoblasts into syncytiotrophoblasts, and thus during differentiation telomerase activity, as well as human telomerase reverse transcriptase (hTERT) expression, is down-regulated. Considering this, it is of interest to investigate whether...

journal_title：Reproductive biomedicine online

authors： Neelima PS,Rao Rekha M,Rama S,Rao AJ

更新日期：2009-06-01 00:00:00

abstract：:Triggering of final oocyte maturation with gonadotrophin-releasing hormone agonist (GnRHa) has previously been shown to prevent ovarian hyperstimulation syndrome (OHSS), but at the same time a detrimental effect on clinical outcome parameters was usually reported. In this prospective, observational, proof-of-concept s...

journal_title：Reproductive biomedicine online

authors： Humaidan P

更新日期：2009-05-01 00:00:00

abstract：:The aim of this study was to investigate the regulation of anti-Müllerian hormone (AMH) blood concentrations in mother and fetus during pregnancy. Serum concentrations of AMH, gonadotrophins, oestradiol and progesterone were measured in pregnant women in the first trimester and AMH concentrations in second-trimester f...

journal_title：Reproductive biomedicine online

authors： Lutterodt M,Byskov AG,Skouby SO,Tabor A,Yding Andersen C

更新日期：2009-05-01 00:00:00

abstract：:Studies suggest Candida albicans infection has a negative effect on sperm function, including fertilizing ability. Assisted reproduction treatment using spermatozoa from a patient with unrecognized C. albicans infection did not result in fertilization. Preliminary evidence suggested an effect on sperm motility and apo...

journal_title：Reproductive biomedicine online

authors： Burrello N,Salmeri M,Perdichizzi A,Bellanca S,Pettinato G,D'Agata R,Vicari E,Calogero AE

更新日期：2009-04-01 00:00:00

abstract：:A total of 52 female Wistar rats were distributed into four groups: non-diabetic (G1) and diabetic (G2) exposed to filtered air; non-diabetic (G3) and diabetic (G4) exposed to cigarette smoke. Diabetes was induced by streptozotocin (40 mg/kg bodyweight, i.v.). Rats were exposed, for 30 min, to filtered air (control) o...

journal_title：Reproductive biomedicine online

authors： de Souza Mda S,Lima PH,Sinzato YK,Rudge MV,Pereira OC,Damasceno DC

更新日期：2009-04-01 00:00:00

abstract：:Congenital bilateral absence of the vas deferens (CBAVD) is a frequent cause of obstructive azoospermia, and caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. A novel TG(13)T(2) allele was identified in a CBAVD patient with no clinical cystic fibrosis phenotype, normal pancrea...

journal_title：Reproductive biomedicine online

authors： Radpour R,Taherzadeh-Fard E,Gourabi H,Aslani S,Vosough Dizaj A,Aslani A

更新日期：2009-03-01 00:00:00

abstract：:Information regarding the growth and development of endometriomas during IVF-intracytoplasmic sperm injection (ICSI) cycles is lacking. In this study, the aim was to estimate the influence of IVF-ICSI on the dimension of these cysts and to assess whether this treatment contributes to the manifestation of new endometri...

journal_title：Reproductive biomedicine online

authors： Benaglia L,Somigliana E,Vighi V,Nicolosi AE,Iemmello R,Ragni G

更新日期：2009-03-01 00:00:00

abstract：:In an attempt to examine the role of human menopausal gonadotrophin (HMG) administration in patients with high basal FSH/LH ratio, patients undergoing at least two IVF cycles, where one included HMG (HMG group) and the other included recombinant FSH (rFSH) only (FSH group), were studied. The use of HMG, in this specif...

journal_title：Reproductive biomedicine online

authors： Orvieto R,Homburg R,Meltcer S,Rabinson J,Anteby EY,Nahum R

更新日期：2009-02-01 00:00:00

abstract：:The effect that gonadotrophin-releasing hormone (GnRH) antagonists exert on endometrial receptivity has not yet been elucidated. GnRH antagonists might directly affect oocytes, the embryo and/or the endometrium. The aim of this study was to investigate the direct effect of GnRH antagonists on the endometrium in oocyte...

journal_title：Reproductive biomedicine online

authors： Prapas N,Tavaniotou A,Panagiotidis Y,Prapa S,Kasapi E,Goudakou M,Papatheodorou A,Prapas Y

更新日期：2009-02-01 00:00:00

abstract：:In terms of treatment outcome, little prognostic power is attributed to day-4 morphology. A day-4 score was applied to 56 patients separating non-compacting embryos from compacting (some areas of compaction) and fully compacted embryos. The latter were further subdivided according to the morphology of compaction. Grad...

journal_title：Reproductive biomedicine online

authors： Ebner T,Moser M,Shebl O,Sommergruber M,Gaiswinkler U,Tews G

更新日期：2009-01-01 00:00:00